Sold By The Ounce,This is a very rare plant and has zero presence online we carry a very limited amount yearly due to its hard to propagate and maintain.We also have a tincture available! Reverse tolerance is true with P.Colorata use daily will increase effects Its a very good Kratom Alternative.

An ethnopharmacological survey showed that home remedies prepared with flowers and fruits of Psychotria colorata are used by Amazonian peasants as pain killers. Psychopharmacological in vivo evaluation of alkaloids obtained from leaves and flowers of this species showed a marked dose-dependent naloxone-reversible analgesic activity, therefore suggesting an opioid-like pharmacological profile. This paper reports an inhibitory effect of P. colorata flower alkaloids on [3H]naloxone binding in rat striata as well as a decrease in adenylate cyclase basal activity. The alkaloids did not affect [3H] GMP-PNP binding. These findings provide a neurochemical basis for the opioid-like activity previously detected in vivo and point to Psychotria alkaloids as a potential source of new bioactive opiate derivatives.

*This is a amazing botanical on the spectrum like kratom from the coffee family.